Sunadarai sune mahimman abubuwa a jikin mutum, suna cikin haɗuwa da homonu da enzymes, suna da mahimmanci don aiwatar da adadi mai yawa na tasirin halittu. Hadadden sunadaran gina jiki an gina su ne daga amino acid.
Leucine shine ɗayan mahimman mahadi a cikin wannan rukuni. Yana nunin muhimman amino acid din da jiki ba zai iya hada kansu ba, amma yake karba daga waje. Ana amfani da Leucine a cikin abinci mai gina jiki, magani, da aikin gona. A masana'antar abinci, an san shi da ƙari E641 L-Leucine kuma ana amfani dashi don haɓaka dandano da ƙanshin abinci.
Binciken amino acid
A karo na farko, leucine ya zama sananne kuma an bayyana tsarin tsarinta ta hanyar masanin sunadarai Henri Braconneau a cikin 1820. A farkon karni na 20, Hermann Emil Fischer ya iya kirkirar wannan mahadi ta hanyar kere-kere. A shekara ta 2007, mujallar Ciwon ta fitar da sakamakon binciken kimiya kan ayyuka da kaddarorin leucine. Kuna iya duba sakamakon da ƙarshen masana kimiyya ta bin hanyar haɗin yanar gizo (ana gabatar da bayanai cikin Turanci).
An gudanar da gwajin a kan berayen dakin gwaje-gwaje. Dabbobin sun kasu kashi biyu. A na farkonsu, beraye sun sami abinci na yau da kullun, kuma a cikin abincin na biyun akwai wadataccen abinci mai ƙiba. Hakanan, an raba kowane rukuni zuwa rukuni-rukuni: a ɗayansu, ana ba dabbobi dabbar miligiram 55 kowace rana, kuma a na biyun, ɓerayen ba su sami ƙarin mahadi ban da abincin da ake son samarwa.
Dangane da sakamakon makonni 15, ya zama cewa dabbobin da aka ciyar da abinci mai ƙima sun sami nauyi. Koyaya, waɗanda suka karɓi ƙarin leucine sun sami 25% ƙasa da waɗanda ba su karɓi amino acid ba a cikin abincinsu.
Bugu da kari, binciken ya nuna cewa dabbobin da aka baiwa leucine sun fi oxygen shan wasu. Wannan yana nufin cewa tsarin rayuwarsu sun kasance da sauri, kuma an ƙona karin adadin kuzari. Hujja ta nuna wa masana kimiyya cewa amino acid yana rage aikin tara kitsen jiki.
Nazarin dakunan gwaje-gwaje na zaren tsoka da adipocytes a cikin farin kayan adipose sun nuna cewa karin shan leucine a jiki yana motsa samar da kwayar halittar furotin wacce ba ta narkewa wanda ke kara kona mai mai tsanani a matakin salula.
A shekarar 2009, masana kimiyya daga Jami'ar Pennsylvania sun sake maimaita gwajin abokan aikinsu. Ana iya samun sakamakon wannan binciken a nan (ana kuma bayar da bayanai a cikin Turanci). Sakamakon masana kimiyya ya tabbata cikakke. An kuma gano cewa shan karamin amino acid ba shi da wani tasiri a kan beraye.
Matsayin ilimin halittu na leucine
Leucine yana taka muhimmiyar rawa a cikin matakai da yawa. Yana aiwatar da ayyuka masu zuwa:
- yana jinkirta tafiyar matakai a cikin tsokoki;
- hanzarta hada ƙwayoyin sunadarai, wanda ke taimakawa wajen gina ƙwayar tsoka;
- yana saukar da sukarin jini;
- yana samar da daidaiton nitrogen da nitrogenous mahadi, wanda ya zama dole don furotin da kumburi metabolism;
- yana hana kira mai yawa na serotonin, wanda ke taimakawa rage gajiya da hanzarta dawowa bayan aiki.
Abun cikin al'ada na leucine a cikin jini yana ƙarfafa garkuwar jiki, yana inganta warkar da rauni, kuma yana hanzarta dawowa daga rauni. Jiki yana amfani da shi azaman tushen makamashi.
Aikace-aikace a wasanni
Tare da tsananin motsa jiki, jiki yana buƙatar ƙarin kayan aiki don gina ƙwayoyin tsoka da cire ƙarfi. A cikin wasanni, musamman horo na ƙarfi kamar ginin jiki, ɗaga ikon jiki, ƙetare jiki, leucine al'ada ce gama gari.
Wajibi ne don rage ƙarfin catabolism da kuma hanzarta aiwatar da ayyukan anabolic. Yawanci, ana ɗaukar amino acid a cikin sifofin karin wasanni wanda ya ƙunshi hadadden BCAA. Ya ƙunshi amino acid masu mahimmanci guda uku - leucine, isoleucine da valine.
A cikin irin waɗannan abubuwan abincin, rabon abubuwan da aka gyara sune 2: 1: 1 (bi da bi, leucine, isomer da valine), wasu masana'antun suna haɓaka abun da ke cikin na farko sau biyu ko ma sau huɗu.
'Yan wasa suna amfani da wannan amino acid don gina tsoka da rage nauyi. Bugu da kari, karin leucine yana kara karfin kuzarin da ake buƙata don haɓaka wasan motsa jiki.
Aikace-aikace a magani
Hakanan ana amfani da shirye-shiryen dauke da Leucine don dalilai na warkewa. An tsara su ne don cututtukan hanta masu tsanani, dystrophy, polioyelitis, neuritis, ƙarancin jini, da wasu larurar lafiyar ƙwaƙwalwa.
A ƙa'ida, ana ba da gudummawar wannan fili tare da ƙwayoyi waɗanda ke ƙunshe da sinadarin glutamic acid da sauran amino acid don haɓaka tasirin warkewa.
Fa'idodin leucine ga jiki sun haɗa da sakamako masu zuwa:
- daidaita aikin hepatocyte;
- ƙarfafa rigakafi;
- rage haɗarin kiba;
- tallafi don ci gaban tsoka daidai;
- hanzari na dawowa bayan aiki na jiki, haɓaka ƙwarewa;
- sakamako mai amfani akan yanayin fata.
Amino acid ana amfani dashi don murmurewar marasa lafiya da ke fama da cutar dystrophy, an tsara shi bayan doguwar azumi. Hakanan ana amfani dashi don kula da marasa lafiya da marasa lafiya tare da hanta cirrhosis. Ana amfani dasu don hanzarta dawowa daga raunin da ya faru, tsoma bakin tiyata, da kuma cikin shirye-shiryen tsufa.
Bukatar yau da kullun
Bukatar babban mutum shine 4-6 g na leucine kowace rana. 'Yan wasa suna buƙatar ƙari kaɗan daga wannan mahaɗin.
- Idan makasudin shine gina ƙwayar tsoka, to ana bada shawarar ɗaukar gram 5-10 a lokacin da bayan horo. Wannan tsarin yana kula da isasshen matakan leucine a cikin jini yayin motsa jiki mai zafi, wanda ke tabbatar da daidaituwar ƙwayar ƙwayar tsoka.
- Idan makasudin dan wasa shine asara, bushewa, to kana bukatar amfani da kari wanda ya kunshi leucine sau 2-4 a rana, a cikin adadin kusan g 15. Ana ɗaukar ƙarin yayin yayin da bayan horo, haka kuma sau 1-2 a rana tsakanin abinci. Wannan makircin yana motsa kuzari kuma yana inganta ƙona mai. A lokaci guda, ana kiyaye ƙwayar tsoka, kuma ana murkushe ayyukan catabolic.
Wuce hanyar yau da kullun na iya haifar da yawan leucine cikin jiki kuma yana da lahani ga lafiya. Yana da kyau a shawarci likita kafin amfani da kowane magani ko kayan abinci masu dauke da wannan amino acid. 'Yan wasa na iya dogaro da ƙwararren mai koyar da ƙwarewa don nemo madaidaiciyar sashi.
Sakamakon rashi da wuce gona da iri a jikin leucine
Leucine muhimmin amino acid ne: saboda haka, yana da mahimmanci a sami wadatar wannan mahaɗan daga waje. Rashin sa a cikin jiki yana haifar da ƙarancin ƙimar nitrogen kuma yana dagula ayyukan hanyoyin rayuwa.
Rashin cutar Leucine yana haifar da ci gaban yara saboda rashin isasshen haɓakar haɓakar hormone. Hakanan, rashin wannan amino acid din yana haifar da ci gaban hypoglycemia. Canje-canje na cututtukan cututtuka suna farawa a cikin kodan, glandar thyroid.
Yawan leucine ma na iya haifar da matsaloli daban-daban. Yawan amfani da wannan amino acid yana taimakawa ci gaban yanayi masu zuwa:
- cututtukan jijiyoyin jiki;
- jihohin da ke cike da matsi;
- ciwon kai;
- hypoglycemia;
- ci gaba da mummunan halayen immunological;
- ƙwayar ƙwayar tsoka.
Tushen Abinci na Leucine
Jiki yana samun wannan amino acid ne daga abinci ko kari na musamman da magunguna - yana da mahimmanci don tabbatar da wadatar wannan mahaɗin.
Ofaya daga cikin magungunan leucine
Don yin wannan, ana ba da shawarar yin amfani da samfuran masu zuwa:
- kwayoyi;
- waken soya;
- wake, wake, gyada;
- cuku (cheddar, parmesan, Switzerland, poshekhonsky);
- kayayyakin kiwo da madara duka;
- turkey;
- jan caviar;
- kifi (herring, hoda mai ruwan hoda, ruwan teku, mackerel, pike perch, pike, cod, pollock);
- naman sa da hanta na naman sa;
- kaza;
- yar tunkiya;
- qwai kaza;
- hatsi (gero, masara, shinkafar ruwan kasa);
- sesame;
- squid;
- kwai foda.
Ana samun leucine a cikin ƙwayoyin sunadarai da keɓaɓɓu da 'yan wasa ke amfani da su.
Contraindications
Wasu ƙarancin halayen rashin gado suna hanawa ga shan leucine.
- Leucinosis (cututtukan Menkes) cuta ce da ke haifar da amino acid na hydrophobic (leucine, isoleucine da valine). An gano wannan ƙwayar cutar a cikin kwanakin farko na rayuwa. Cutar na buƙatar nadin abinci na musamman, wanda ba a cire abincin furotin. Ana maye gurbinsa da furotin hydrolysates, wanda bashi da hadadden BCAA amino acid. Alamar halayyar leucinosis shine takamammen ƙamshin fitsari, wanda yake tuna ƙamshi na ƙonewar sukari ko maple syrup.
- Hoton asibiti kamar na cututtukan Menkes shima ana bayar dashi ta wata cuta wacce aka ƙaddara ta hanyar haihuwa - isovaleratacidemia. Wannan wata cuta ce ta keɓaɓɓen cutar leucine, wanda yakamata a cire shan wannan amino acid a jiki.
Yawancin halayen biochemical a cikin jiki ba zai yiwu ba tare da leucine. Ana iya samo shi daga kayan abinci a cikin adadin da ake buƙata kawai tare da daidaitaccen abinci, kodayake, tare da ƙwazo na motsa jiki, yawan amino acid yana ƙaruwa sosai.
Shan leucine yana da mahimmanci ga yan wasan da ke neman hanzarta ginin tsoka ta hanyar rage saurin abubuwan da ake gudanarwa. Shan amino acid zai taimaka maka rage nauyi yayin kiyaye karfin tsoka ba canzawa.
